The human health effects of exposure to polybrominated biphenyls

The human health effects of exposure to polybrominated biphenyls.

The Human Health Effects of Exposure to Polybrominated Biphenyls. STROSS, J. K., SMOKLER, I. A., ISBISTER, J., AND WILCOX, K. R. (1981). Toxicol. Appl. Pharmacol. 58, 145-150. Polybrominated biphenyls (PBB) were inadvertently introduced into the food chain in Michigan in 1973. Fifty-one people with known exposure to PBB were studied. Twenty-three farmers with disabling health complaints, and 28...

Human exposure to polychorinated biphenyls and polybrominated biphenyls

Although the polychlorinated biphenyls (PCBs) have been used in a wide variety of industrial applications in the U. S. from 1930 until 1970, when their distribution was voluntarily restricted to closed systems, there is scant information on human exposure to adverse human health effects in the U. S. In the U. S., minimal human exposure of the population to PCBs is limited to food, air, and wate...

Cutaneous effects of exposure to polybrominated biphenyls (PBBs): the Michigan PBB incident.

In 1973 an environmental accident occurred in northern Michigan in which 1000-2000 pounds of the toxic fire retardant polybrominated biphenyl (PBB) was added to the livestock food supply of much of northern Michigan. PBB is highly lipophilic. poorly metabolized, and biocumulative. It subsequently entered the human food chain of the entire state of Michigan. Health effects were noted in contamin...

Polybrominated biphenyls 74 Hazard assessment of Polybrominated biphenyls

Incidence of thyroid disease following exposure to polybrominated biphenyls and polychlorinated biphenyls, Michigan, 1974-2006.

Thyroid hormones, which influence body metabolism and development, could be affected by persistent organic pollutants. We sought to examine the relationship between polybrominated biphenyls (PBBs) and polychlorinated biphenyls (PCBs) and thyroid disease. We employed incidence density sampling to perform a nested case control analysis of the Michigan Long-Term PBB Cohort. Cohort members (n=3333)...